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5'-Triphosphate RNA Is the Ligand for RIG-I

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Science  10 Nov 2006:
Vol. 314, Issue 5801, pp. 994-997
DOI: 10.1126/science.1132505

Article Information

vol. 314 no. 5801 994-997

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 14, 2006
  • Accepted for publication September 18, 2006
  • .

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Author Information

  1. Veit Hornung1,
  2. Jana Ellegast1,
  3. Sarah Kim1,
  4. Krzysztof Brzózka3,
  5. Andreas Jung2,
  6. Hiroki Kato2,
  7. Hendrik Poeck1,
  8. Shizuo Akira2,
  9. Karl-Klaus Conzelmann3,
  10. Martin Schlee4,
  11. Stefan Endres1,
  12. Gunther Hartmann4,*
  1. 1 Division of Clinical Pharmacology, Department of Internal Medicine, University of Munich, 80336 Munich, Germany.
  2. 2 Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita 565–0871, Osaka, Japan.
  3. 3 Department of Virology, Max von Pettenkofer Institute and Gene Center, University of Munich, 81377 Munich, Germany.
  4. 4 Division of Clinical Pharmacology, University Hospital, University of Bonn, 53105 Bonn, Germany.
  1. * To whom correspondence should be addressed. E-mail: gunther.hartmann{at}ukb.uni-bonn.de

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