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Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism

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Science  17 Nov 2006:
Vol. 314, Issue 5802, pp. 1144-1147
DOI: 10.1126/science.1131399

Article Information

vol. 314 no. 5802 1144-1147

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History: 
  • Received for publication June 16, 2006
  • Accepted for publication September 28, 2006

Author Information

  1. Achillefs N. Kapanidis1,2,,
  2. Emmanuel Margeat1,*,
  3. Sam On Ho1,
  4. Ekaterine Kortkhonjia1,3,
  5. Shimon Weiss1,,
  6. Richard H. Ebright3,
  1. 1 Department of Chemistry and Biochemistry and Department of Physiology, University of California, Los Angeles, CA 90095, USA.
  2. 2 Clarendon Laboratory, Department of Physics, and IRC in Bionanotechnology, University of Oxford, Oxford OX1 3PU, UK.
  3. 3 Howard Hughes Medical Institute, Department of Chemistry, and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
  1. To whom correspondence should be addressed. E-mail: a.kapanidis1{at}physics.ox.ac.uk, sweiss{at}chem.ucla.edu, ebright{at}waksman.rutgers.edu
  • * Present address: Centre de Biochimie Structurale. CNRS UMR 5048. INSERM UMR 554. Université Montpellier I, 29 rue de Navacelles, 34090 Montpellier cedex, France.

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