Review

Recombination and the Nature of Bacterial Speciation

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Science  26 Jan 2007:
Vol. 315, Issue 5811, pp. 476-480
DOI: 10.1126/science.1127573

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  • Reponse to A. Jeltsch’s E-Letter

    We agree that it has been known for some time that restriction/modification (RM) systems can form a barrier to recombination, and that other authors (1) including Jeltsch (2) have suggested they could be important in causing reproductive isolation. However, we are unaware of any data that actively implicate them in the process of speciation, as opposed to hypothesizing that they could be involved. RM systems a...

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    Competing Interests: None declared.
  • Role of Restriction/Modification System in Bacterial Speciation

    Fraser et al. state that restriction/modification systems (RM-systems) have not yet been implicated in the process of bacterial speciation. This model has already been described in detail in 2003 (1). It proposes that constituting a barrier to horizontal gene transfer is one central biological function of restriction/modification systems. Different RM-systems present in a single bacterial species divide it int...

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    Competing Interests: None declared.

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