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A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants

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Science  01 Jun 2007:
Vol. 316, Issue 5829, pp. 1341-1345
DOI: 10.1126/science.1142382

Article Information

vol. 316 no. 5829 1341-1345

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History: 
  • Received for publication March 12, 2007
  • Accepted for publication April 20, 2007
  • .

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Author Information

  1. Laura J. Scott1,
  2. Karen L. Mohlke2,
  3. Lori L. Bonnycastle3,
  4. Cristen J. Willer1,
  5. Yun Li1,
  6. William L. Duren1,
  7. Michael R. Erdos3,
  8. Heather M. Stringham1,
  9. Peter S. Chines3,
  10. Anne U. Jackson1,
  11. Ludmila Prokunina-Olsson3,
  12. Chia-Jen Ding1,
  13. Amy J. Swift3,
  14. Narisu Narisu3,
  15. Tianle Hu1,
  16. Randall Pruim4,
  17. Rui Xiao1,
  18. Xiao-Yi Li1,
  19. Karen N. Conneely1,
  20. Nancy L. Riebow3,
  21. Andrew G. Sprau3,
  22. Maurine Tong3,
  23. Peggy P. White1,
  24. Kurt N. Hetrick5,
  25. Michael W. Barnhart5,
  26. Craig W. Bark5,
  27. Janet L. Goldstein5,
  28. Lee Watkins5,
  29. Fang Xiang1,
  30. Jouko Saramies6,
  31. Thomas A. Buchanan7,
  32. Richard M. Watanabe8,9,
  33. Timo T. Valle10,
  34. Leena Kinnunen10,11,
  35. Gonçalo R. Abecasis1,
  36. Elizabeth W. Pugh5,
  37. Kimberly F. Doheny5,
  38. Richard N. Bergman9,
  39. Jaakko Tuomilehto10,11,12,
  40. Francis S. Collins3,*,
  41. Michael Boehnke1,*
  1. 1 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  2. 2 Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  3. 3 Genome Technology Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA.
  4. 4 Department of Mathematics and Statistics, Calvin College, Grand Rapids, MI 49546, USA.
  5. 5 Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA.
  6. 6 Savitaipale Health Center, 54800 Savitaipale, Finland.
  7. 7 Division of Endocrinology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
  8. 8 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
  9. 9 Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
  10. 10 Diabetes Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, 00300 Helsinki, Finland.
  11. 11 Department of Public Health, University of Helsinki, 00014 Helsinki, Finland.
  12. 12 South Ostrobothnia Central Hospital, 60220 Seinäjoki, Finland.
  1. * To whom correspondence should be addressed. E-mail: boehnke{at}umich.edu (M.B.); francisc{at}mail.nih.gov (F.S.C.)

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