Report

Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit

See allHide authors and affiliations

Science  13 Jul 2007:
Vol. 317, Issue 5835, pp. 239-242
DOI: 10.1126/science.1135394

Article Information

vol. 317 no. 5835 239-242

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 21, 2006
  • Accepted for publication May 31, 2007
  • .

Author Information

  1. Nabil Miled1,*,,
  2. Ying Yan2,*,
  3. Wai-Ching Hon1,
  4. Olga Perisic1,
  5. Marketa Zvelebil3,
  6. Yuval Inbar4,
  7. Dina Schneidman-Duhovny4,
  8. Haim J. Wolfson4,
  9. Jonathan M. Backer2,,
  10. Roger L. Williams1,
  1. 1 Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
  2. 2 Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY10461, USA.
  3. 3 Ludwig Institute for Cancer Research, University College London, London W1W 7BS, UK.
  4. 4 School of Computer Science, The Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
  1. To whom correspondence should be addressed. E-mail: rlw{at}mrc-lmb.cam.ac.uk (R.L.W.); backer{at}aecom.yu.edu (J.M.B.)
  • * These authors contributed equally to this work.

  • Present address: Laboratoire de Biochimie et de Génie Enzymatique des Lipases, Ecole Nationale d'Ingenieurs Sfax, Route Soukra BPW, 3038 Sfax, Tunisia.

Altmetric

Article usage

Article usage: July 2007 to August 2019

AbstractFullPdf
Jul 2007191810481845
Aug 2007201329418
Sep 200769216188
Oct 200768199214
Nov 200756145106
Dec 20074910197
Jan 20084711684
Feb 2008289190
Mar 20084311889
Apr 2008357259
May 2008367861
Jun 2008407449
Jul 2008387147
Aug 2008275337
Sep 2008447556
Oct 2008467552
Nov 2008365850
Dec 2008273932
Jan 2009193649
Feb 2009433633
Mar 2009464746
Apr 2009223431
May 2009404544
Jun 2009294434
Jul 2009242421
Aug 2009224025
Sep 2009283636
Oct 2009383836
Nov 2009334533
Dec 2009382436
Jan 2010494136
Feb 2010415135
Mar 2010484032
Apr 2010463226
May 2010363533
Jun 2010325430
Jul 2010353031
Aug 2010442022
Sep 2010712137
Oct 2010763432
Nov 2010602823
Dec 2010641317
Jan 2011871723
Feb 2011662615
Mar 2011872427
Apr 2011852434
May 201167715
Jun 2011871920
Jul 201173819
Aug 201172715
Sep 20111341629
Oct 20111231626
Nov 20111401623
Dec 2011104516
Jan 201280524
Feb 20121052026
Mar 20121271421
Apr 2012110817
May 20121061525
Jun 201256514
Jul 2012551315
Aug 2012402318
Sep 2012622020
Oct 2012582317
Nov 20121061380
Dec 2012521517
Jan 2013821921
Feb 2013821518
Mar 20139277
Apr 20131042024
May 2013542326
Jun 2013413114
Jul 20134878
Aug 2013892018
Sep 2013801818
Oct 2013962523
Nov 2013652621
Dec 2013691512
Jan 2014481512
Feb 2014711813
Mar 2014841412
Apr 2014872620
May 2014682318
Jun 2014652214
Jul 2014562626
Aug 2014442116
Sep 2014821317
Oct 20141152222
Nov 20141321311
Dec 20141231919
Jan 2015751720
Feb 2015542314
Mar 2015702822
Apr 2015751910
May 2015522112
Jun 2015521513
Jul 2015301211
Aug 201557810
Sep 2015361314
Oct 2015762018
Nov 2015701915
Dec 20157974
Jan 201660126
Feb 201610247
Mar 2016801025
Apr 2016103615
May 20165179
Jun 20167857
Jul 2016601012
Aug 201656715
Sep 201654616
Oct 201656613
Nov 201649914
Dec 20165754
Jan 201779814
Feb 2017591118
Mar 2017591716
Apr 201762514
May 2017371015
Jun 2017411510
Jul 20173328
Aug 201753512
Sep 201769818
Oct 2017771611
Nov 201758138
Dec 2017542016
Jan 2018691721
Feb 2018412119
Mar 2018652415
Apr 2018512313
May 20184389
Jun 201847149
Jul 201840918
Aug 2018272116
Sep 201836278
Oct 2018362512
Nov 201838278
Dec 201826135
Jan 2019322415
Feb 201937145
Mar 2019452711
Apr 2019252710
May 2019412415
Jun 2019311511
Jul 2019341915
Aug 201914139