Contents
Vol 317, Issue 5837
Contents
This Week in Science
Editorial
Editors' Choice
Departments
Products & Materials
News of the Week
ScienceScope
Random Samples
Newsmakers
News Focus
Letters
Books
Education Forum
Perspectives
Association Affairs
Reviews
Brevia
- AAV Vector Integration Sites in Mouse Hepatocellular Carcinoma
A virus that has shown promise as a vector for human gene therapy causes liver tumors in neonatal mice.
Research Articles
- Free-Drifting Icebergs: Hot Spots of Chemical and Biological Enrichment in the Weddell Sea
Trace elements and iron released from free-drifting Antarctic icebergs stimulate local productivity that enhances carbon sequestration in the Southern Ocean.
- The Product Space Conditions the Development of Nations
Network analysis of the products made by rich and poor countries show that movement toward higher-profit products may be restricted for much of the developing world.
Reports
- Single-Atom Single-Photon Quantum Interface
A sequence of laser pulses targeted on a single atom trapped in a cavity can generate a source of entangled photon pairs.
- Porous Semiconducting Gels and Aerogels from Chalcogenide Clusters
The reaction of clusters containing sulfur or selenium with a platinum complex yields highly porous gels that can efficiently absorb heavy metals from water.
- Stabilization of Labile Carbonyl Addition Intermediates by a Synthetic Receptor
A synthetic molecular basket stabilizes a short-lived intermediate species in an organic reaction for minutes to hours, allowing it to be probed and identified.
- A Powerful Chiral Counterion Strategy for Asymmetric Transition Metal Catalysis
Pairing an achiral cationic gold complex with a chiral phosphate anion leads to efficient asymmetric catalysis of previously intractable organic reactions.
- A Cambrian Peak in Morphological Variation Within Trilobite Species
In trilobites, the morphology of individual species shows the greatest changes soon after their origin, influencing the course of early evolution in the group.
- Four Climate Cycles of Recurring Deep and Surface Water Destabilizations on the Iberian Margin
Alternating penetration of deep ocean waters derived from the two polar regions to low latitudes drove century-to-millennial climate changes for at least the past 400,000 years.
- Ethylene Modulates Stem Cell Division in the Arabidopsis thaliana Root
Stem cell proliferation in a niche within developing roots is limited by the gaseous hormone ethylene.
- Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein
The structure of a human membrane protein involved in biosynthesis of the inflammation-related leukotrienes may help guide the development of therapeutics.
- Spring-Loaded Mechanism of DNA Unwinding by Hepatitis C Virus NS3 Helicase
A helicase enzyme unwinds DNA in steps three base pairs long that periodically release the tension resulting from translocation of the helicase's motor domain along the DNA.
- Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease
An inhibitor of a microtubule deacetylase protects dopamine-containing cells and can rescue Drosophila from the toxicity of a protein aggregate associated with Parkinson's disease.
- The Near Eastern Origin of Cat Domestication
The domestic cat and several of its closely related wild relatives originated in the Fertile Crescent over 100,000 years ago, earlier than had been thought.
- Candidatus Chloracidobacterium thermophilum: An Aerobic Phototrophic Acidobacterium
A distinctive, oxygen-tolerant photosynthetic bacterium has been identified in a metagenomic study of hot-spring communities in Yellowstone National Park.
- Noise in Gene Expression Determines Cell Fate in Bacillus subtilis
Bacteria that show more random fluctuations in gene expression are especially likely to switch to an alternative phenotype in which they can take up foreign genetic material.
- Rapid Synthesis and Synaptic Insertion of GluR2 for mGluR-LTD in the Ventral Tegmental Area
A decrease in the effectiveness of synapses in a particular brain region is caused by replacement of one glutamate receptor subtype with a less efficient one.
Technical Comments
