Fluorine in Pharmaceuticals: Looking Beyond Intuition

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Science  28 Sep 2007:
Vol. 317, Issue 5846, pp. 1881-1886
DOI: 10.1126/science.1131943

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  • Fluorine in Corticosteroids

    This Review is a comprehensive overview on the most important aspects of fluorine substituents on the receptor binding of pharmaceuticals ("Fluorine in pharmaceuticals: Looking beyond intuition," by K. Mueller et al., 28 September 2007, p. 1881). Interestingly, however, an important class in which the effects of fluorination have long been investigated are not mentioned at all: corticosteroids, including gluco- and min...

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    Competing Interests: None declared.

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