Research Article

High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor

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Science  23 Nov 2007:
Vol. 318, Issue 5854, pp. 1258-1265
DOI: 10.1126/science.1150577

Article Information

vol. 318 no. 5854 1258-1265

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History: 
  • Received for publication September 17, 2007
  • Accepted for publication October 11, 2007
  • .

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Author Information

  1. Vadim Cherezov1,*,
  2. Daniel M. Rosenbaum2,*,
  3. Michael A. Hanson1,
  4. Søren G. F. Rasmussen2,
  5. Foon Sun Thian2,
  6. Tong Sun Kobilka2,
  7. Hee-Jung Choi2,3,
  8. Peter Kuhn4,
  9. William I. Weis2,3,
  10. Brian K. Kobilka2,,
  11. Raymond C. Stevens1,
  1. 1 Department of Molecular Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2 Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  3. 3 Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  4. 4 Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  1. To whom correspondence should be addressed. E-mail: stevens{at}scripps.edu (R.C.S.); kobilka{at}stanford.edu (B.K.K.)
  • * These authors contributed equally to this work.

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