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Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes

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Science  08 Feb 2008:
Vol. 319, Issue 5864, pp. 819-821
DOI: 10.1126/science.1149250

Article Information

vol. 319 no. 5864 819-821

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History: 
  • Received for publication August 15, 2007
  • Accepted for publication December 21, 2007

Author Information

  1. Raga Krishnakumar1,2,*,
  2. Matthew J. Gamble1,*,
  3. Kristine M. Frizzell1,2,
  4. Jhoanna G. Berrocal1,2,
  5. Miltiadis Kininis1,3,
  6. W. Lee Kraus1,2,3,4,
  1. 1 Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
  2. 2 Graduate Field of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, NY 14853, USA.
  3. 3 Graduate Field of Genetics and Development, Cornell University, Ithaca, NY 14853, USA.
  4. 4 Department of Pharmacology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  1. To whom correspondence should be addressed at Department of Molecular Biology and Genetics, Cornell University, 465 Biotechnology Building, Ithaca, NY 14853, USA. E-mail: wlk5{at}cornell.edu
  • * These authors contributed equally to this work.

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