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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

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Science  21 Mar 2008:
Vol. 319, Issue 5870, pp. 1668-1672
DOI: 10.1126/science.1154584

Article Information

vol. 319 no. 5870 1668-1672

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History: 
  • Received for publication December 26, 2007
  • Accepted for publication February 19, 2008
  • .

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Author Information

  1. Jemeen Sreedharan1,*,
  2. Ian P. Blair3,4,*,
  3. Vineeta B. Tripathi1,*,
  4. Xun Hu1,
  5. Caroline Vance1,
  6. Boris Rogelj1,
  7. Steven Ackerley1,2,
  8. Jennifer C. Durnall3,
  9. Kelly L. Williams3,
  10. Emanuele Buratti5,
  11. Francisco Baralle5,
  12. Jacqueline de Belleroche6,
  13. J. Douglas Mitchell7,
  14. P. Nigel Leigh1,
  15. Ammar Al-Chalabi1,
  16. Christopher C. Miller1,2,
  17. Garth Nicholson3,4,8,*,
  18. Christopher E. Shaw1,*,
  1. 1 Department of Clinical Neuroscience, King's College London, Medical Research Council (MRC) Centre for Neurodegeneration Research, and Institute of Psychiatry, London, SE5 8AF, UK.
  2. 2 Department of Neuroscience, King's College London, MRC Centre for Neurodegeneration Research, and Institute of Psychiatry, London, SE5 8AF, UK.
  3. 3 Northcott Neuroscience Laboratory, Australian and New Zealand Army Corps (ANZAC) Research Institute, Concord, NSW, 2137, Australia.
  4. 4 Faculty of Medicine, University of Sydney, Sydney, NSW, 2139, Australia.
  5. 5 International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34012 Trieste, Italy.
  6. 6 Division of Neurosciences and Mental Health, Faculty of Medicine, Imperial College London, and Charing Cross Hospital, London, W6 8RF, UK.
  7. 7 Department of Neurology, Royal Preston Hospital, Preston, PR2 9HT, UK.
  8. 8 Molecular Medicine Laboratory, Concord Repatriation General Hospital, Concord, NSW, 2139, Australia.
  1. To whom correspondence should be addressed. E-mail: chris.shaw{at}iop.kcl.ac.uk
  • * These authors contributed equally to this work.

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