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Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels

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Science  22 Aug 2008:
Vol. 321, Issue 5892, pp. 1081-1084
DOI: 10.1126/science.1158013

Article Information

vol. 321 no. 5892 1081-1084

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History: 
  • Received for publication March 19, 2008
  • Accepted for publication July 3, 2008
  • .

Author Information

  1. Ofer Feinerman1,*,
  2. Joël Veiga1,*,
  3. Jeffrey R. Dorfman1,,
  4. Ronald N. Germain2,
  5. Grégoire Altan-Bonnet1,
  1. 1 ImmunoDynamics Group, Program in Computational Biology and Immunology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 460, New York, NY 10065, USA.
  2. 2 Lymphocyte Biology Section, Laboratory of Immunology, Program in Systems Immunology and Infectious Disease Modeling, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Building 10, Room 11N311, 10 Center Drive, MSC-1892, Bethesda, MD 20892-1892, USA.
  1. To whom correspondence should be addressed. E-mail: altanbonnet{at}cbio.mskcc.org
  • * These authors contributed equally to this work.

  • Present address: Seattle Biomedical Research Institute, 307 Westlake Avenue N, Suite 500, Seattle, WA 98109-5219, USA.

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