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Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A

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Science  19 Dec 2008:
Vol. 322, Issue 5909, pp. 1839-1842
DOI: 10.1126/science.1165409

Article Information

vol. 322 no. 5909 1839-1842

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Print ISSN: 
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History: 
  • Received for publication September 3, 2008
  • Accepted for publication November 12, 2008
  • .

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Author Information

  1. Vijay G. Sankaran1,2,
  2. Tobias F. Menne1,
  3. Jian Xu1,
  4. Thomas E. Akie1,
  5. Guillaume Lettre3,4,
  6. Ben Van Handel5,
  7. Hanna K. A. Mikkola5,
  8. Joel N. Hirschhorn3,4,
  9. Alan B. Cantor1,
  10. Stuart H. Orkin1,2,6,*
  1. 1 Division of Hematology/Oncology, Children's Hospital Boston, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
  2. 2 Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  3. 3 Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  4. 4 Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital Boston, Boston, MA 02115, USA.
  5. 5 Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
  6. 6 Howard Hughes Medical Institute, Boston, MA 02115, USA.
  1. * To whom correspondence should be addressed. E-mail: stuart_orkin{at}dfci.harvard.edu

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