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AMPylation of Rho GTPases by Vibrio VopS Disrupts Effector Binding and Downstream Signaling

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Science  09 Jan 2009:
Vol. 323, Issue 5911, pp. 269-272
DOI: 10.1126/science.1166382

Article Information

vol. 323 no. 5911 269-272

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 25, 2008
  • Accepted for publication November 14, 2008
  • .

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Author Information

  1. Melanie L. Yarbrough1,
  2. Yan Li2,3,
  3. Lisa N. Kinch4,
  4. Nick V. Grishin4,
  5. Haydn L. Ball2,3,
  6. Kim Orth1,*
  1. 1 Department of Molecular Biology, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2 Protein Chemistry Technology Center, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3 Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4 Howard Hughes Medical Institute and Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  1. * To whom correspondence should be addressed. E-mail: kim.orth{at}utsouthwestern.edu

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