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Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

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Science  20 Feb 2009:
Vol. 323, Issue 5917, pp. 1074-1077
DOI: 10.1126/science.1166859

Article Information

vol. 323 no. 5917 1074-1077

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History: 
  • Received for publication October 6, 2008
  • Accepted for publication December 16, 2008

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Author Information

  1. Dengke K. Ma1,2,*,,
  2. Mi-Hyeon Jang1,3,*,
  3. Junjie U. Guo1,2,
  4. Yasuji Kitabatake1,3,
  5. Min-lin Chang1,3,
  6. Nattapol Pow-anpongkul1,
  7. Richard A. Flavell4,
  8. Binfeng Lu5,
  9. Guo-li Ming1,2,3,
  10. Hongjun Song1,2,3,
  1. 1 Institute for Cell Engineering, Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, MD 21205, USA.
  2. 2 The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, MD 21205, USA.
  3. 3 Department of Neurology, Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, MD 21205, USA.
  4. 4 Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA.
  5. 5 Department of Immunology, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15261, USA.
  1. To whom correspondence should be addressed. E-mail: shongju1{at}jhmi.edu (H.S.); dma2{at}jhmi.edu (D.K.M.)
  • * These authors contributed equally to this work.

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