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A Role for RNAi in the Selective Correction of DNA Methylation Defects

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Science  20 Mar 2009:
Vol. 323, Issue 5921, pp. 1600-1604
DOI: 10.1126/science.1165313

Article Information

vol. 323 no. 5921 1600-1604

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History: 
  • Received for publication September 2, 2008
  • Accepted for publication January 16, 2009

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Author Information

  1. Felipe Karam Teixeira1,2,
  2. Fabiana Heredia1,
  3. Alexis Sarazin2,
  4. François Roudier1,2,
  5. Martine Boccara1,2,
  6. Constance Ciaudo3,4,
  7. Corinne Cruaud5,
  8. Julie Poulain5,
  9. Maria Berdasco6,
  10. Mario F. Fraga6,*,
  11. Olivier Voinnet3,
  12. Patrick Wincker5,
  13. Manel Esteller6,
  14. Vincent Colot1,2,
  1. 1 Unité de Recherche en Génomique Végétale, CNRS UMR 8114, Institut National de la Recherche Argonomique UMR 1165, Université d'Evry Val d'Essonne, 91057 Evry Cedex, France.
  2. 2 CNRS UMR 8186, Département de Biologie, Ecole Normale Supérieure, 75230 Paris Cedex 05, France.
  3. 3 Institut de Biologie Moléculaire des Plantes, CNRS Unité Propre de Recherche 2357, 67084 Strasbourg Cedex, France.
  4. 4 CNRS UMR 218, Institut Curie, 75248 Paris Cedex 05, France.
  5. 5 Génoscope, Commissariat à L'Energie Atomique–Institut de Génomique, 91057 Evry Cedex, France.
  6. 6 Laboratorio de Epigenética del Cáncer, Centro Nacional de Investigaciones Oncológicas, 28029 Madrid, Spain.
  1. To whom correspondence should be addressed. E-mail: colot{at}biologie.ens.fr
  • * Present address: Immunología y Oncología, Centro Nacional Biotecnología, Consejo Superior de Investigaciones Científicas, Cantoblanco, 28049 Madrid, Spain.

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