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Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

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Science  18 Sep 2009:
Vol. 325, Issue 5947, pp. 1555-1559
DOI: 10.1126/science.1174229

Article Information

vol. 325 no. 5947 1555-1559

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 30, 2009
  • Accepted for publication July 29, 2009
  • .

Article Versions

Author Information

  1. Jihye Yun1,
  2. Carlo Rago1,
  3. Ian Cheong1,
  4. Ray Pagliarini1,*,
  5. Philipp Angenendt1,
  6. Harith Rajagopalan1,,
  7. Kerstin Schmidt1,
  8. James K. V. Willson2,
  9. Sandy Markowitz3,
  10. Shibin Zhou1,
  11. Luis A. Diaz Jr1,
  12. Victor E. Velculescu1,
  13. Christoph Lengauer1,,
  14. Kenneth W. Kinzler1,
  15. Bert Vogelstein1,§ and
  16. Nickolas Papadopoulos1
  1. 1The Ludwig Center for Cancer Genetics and Therapeutics and The Howard Hughes Medical Institute at the Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA.
  2. 2Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Department of Medicine and Ireland Cancer Center, Case Western Reserve University and Case Medical Center of University Hospitals of Cleveland and Howard Hughes Medical Institute, Cleveland, OH 44106, USA.
  1. §To whom correspondence should be addressed. E-mail: vogelbe{at}jhmi.edu

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