16 October 2009
Vol 326, Issue 5951

About The Cover

Cover image expansion

COVER A frontal view of the fly brain (blue) showing two groups of dopamine-producing neurons pseudocolored green and magenta. The magenta neurons are engineered to express a light-sensitive protein. Optical signals (symbolized by a magenta beam of light) can selectively report and control the activity of these cells. Miesenböck (page 395) reviews the emerging field of optogenetics in a special section on advances in neuroscience methods starting on page 385. Confocal images: Adam Claridge-Chang; photomontage: Robert Roorda and Gero Miesenböck