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Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

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Science  28 May 2010:
Vol. 328, Issue 5982, pp. 1168-1172
DOI: 10.1126/science.1185723

Article Information

vol. 328 no. 5982 1168-1172

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 8, 2009
  • Accepted for publication April 5, 2010
  • .

Author Information

  1. Tanja Schneider1,
  2. Thomas Kruse2,
  3. Reinhard Wimmer3,
  4. Imke Wiedemann1,
  5. Vera Sass1,
  6. Ulrike Pag1,
  7. Andrea Jansen1,
  8. Allan K. Nielsen4,
  9. Per H. Mygind4,
  10. Dorotea S. Raventós4,
  11. Søren Neve4,
  12. Birthe Ravn4,
  13. Alexandre M. J. J. Bonvin5,
  14. Leonardo De Maria4,
  15. Anders S. Andersen2,4,
  16. Lora K. Gammelgaard4,
  17. Hans-Georg Sahl1 and
  18. Hans-Henrik Kristensen4,*
  1. 1Pharmaceutical Microbiology Section, Institute for Medical Microbiology, Immunology, and Parasitology, University of Bonn, D-53115 Bonn, Germany.
  2. 2Statens Serum Institut, 2300 Copenhagen S, Denmark.
  3. 3Department of Biotechnology, Chemistry, and Environmental Engineering, Aalborg University, DK-9000 Aalborg, Denmark.
  4. 4Novozymes AS, DK-2880 Bagsvaerd, Denmark.
  5. 5Department of Chemistry, Faculty of Science, Utrecht University, 3584 CH Utrecht, Netherlands.
  1. *To whom correspondence should be addressed. E-mail: hahk{at}novozymes.com

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