Report

Focal Lesions of Human Hippocampal CA1 Neurons in Transient Global Amnesia Impair Place Memory

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Science  11 Jun 2010:
Vol. 328, Issue 5984, pp. 1412-1415
DOI: 10.1126/science.1188160

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  • Response to L. R. Squire and S. A. Small's E-Letter

    L. R. Squire and S. A. Small raise some interesting points regarding our Report on spatial memory deficits in patients with a transient global amnesia (TGA); a study that would not have been possible without the seminal work by Squire on the functional anatomy of memory ("Focal lesions of human hippocampal CA1 neurons in transient global amnesia impair place memory," 11 June 2010, p. 1412).

    However, Squire and Small que...

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    Competing Interests: None declared.
  • Do CA1 Neurons Store Spatial Memory?

    T. Bartsch et al.'s interesting Report on transient global amnesia (TGA) shows that MRI lesions, detected with diffusion-weighted and T2-weighted images, appear selectively in the CA1 region of the hippocampus ("Focal lesions of human hippocampal CA1 neurons in transient global amnesia impair place memory," 11 June 2010, p. 1412). In addition to other verbal and nonverbal memory deficits, the TGA patients were reported...

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    Competing Interests: None declared.

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