Research Article

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

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Science  13 Aug 2010:
Vol. 329, Issue 5993, pp. 811-817
DOI: 10.1126/science.1192819

Article Information

vol. 329 no. 5993 811-817

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History: 
  • Received for publication May 25, 2010
  • Accepted for publication July 1, 2010

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Author Information

  1. Tongqing Zhou1,
  2. Ivelin Georgiev1,*,
  3. Xueling Wu1,*,
  4. Zhi-Yong Yang1,*,
  5. Kaifan Dai1,
  6. Andrés Finzi2,
  7. Young Do Kwon1,
  8. Johannes F. Scheid3,
  9. Wei Shi1,
  10. Ling Xu1,
  11. Yongping Yang1,
  12. Jiang Zhu1,
  13. Michel C. Nussenzweig3,
  14. Joseph Sodroski2,4,
  15. Lawrence Shapiro1,5,
  16. Gary J. Nabel1,
  17. John R. Mascola1,
  18. Peter D. Kwong1,
  1. 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  2. 2Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Pathology, Division of AIDS, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Laboratory of Molecular Immunology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.
  4. 4Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
  5. 5Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
  1. To whom correspondence should be addressed. E-mail: pdkwong{at}nih.gov
  1. * These authors contributed equally to this work.

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