Research Article

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

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Science  19 Nov 2010:
Vol. 330, Issue 6007, pp. 1066-1071
DOI: 10.1126/science.1194396

Article Information

vol. 330 no. 6007 1066-1071

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History: 
  • Received for publication June 29, 2010
  • Accepted for publication September 2, 2010

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Author Information

  1. Beili Wu1,
  2. Ellen Y. T. Chien1,
  3. Clifford D. Mol1,
  4. Gustavo Fenalti1,
  5. Wei Liu1,
  6. Vsevolod Katritch2,
  7. Ruben Abagyan2,
  8. Alexei Brooun3,
  9. Peter Wells3,
  10. F. Christopher Bi3,
  11. Damon J. Hamel2,
  12. Peter Kuhn1,
  13. Tracy M. Handel2,
  14. Vadim Cherezov1 and
  15. Raymond C. Stevens1,*
  1. 1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  2. 2Skaggs School of Pharmacy and Pharmaceutical Sciences, and San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093, USA.
  3. 3Pfizer Worldwide Research and Development, 10770 Science Center Drive, San Diego, CA 92121, USA.
  1. *To whom correspondence should be addressed. E-mail: stevens{at}scripps.edu

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