21 January 2011
Vol 331, Issue 6015

About The Cover

Cover image expansion

COVER False-colored scanning electron micrograph showing the proximal colon of germ-free mice colonized with bacteria of the genus Clostridium (average length ~ 3.5 micrometers). Clostridium species indigenous to the mouse colon stimulate intestinal epithelial cells to induce regulatory T cells, which contribute to the suppression of unfavorable inflammation and allergic responses. See page 337. Image: Kenya Honda, Department of Immunology, University of Tokyo