15 April 2011
Vol 332, Issue 6027

About The Cover

Cover image expansion

COVER Schematic representations of DNA nanostructures with complex curvatures including two-dimensional arrangements of concentric rings and three-dimensional shapes, including a nanoflask 70 nanometers tall and 40 nanometers wide (DNA molecule is not shown to scale). On page 342, Han et al. describe the creation of these structures using a DNA origami folding technique in which double-helical DNA is bent to follow the rounded contours of the target object. Image: Dongran Han and Hao Yan, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University