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Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

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Science  15 Apr 2011:
Vol. 332, Issue 6027, pp. 358-361
DOI: 10.1126/science.1192149

Article Information

vol. 332 no. 6027 358-361

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 11, 2010
  • Accepted for publication March 4, 2011
  • .

Author Information

  1. Tammy M. Holm1,*,
  2. Jennifer P. Habashi1,2,*,
  3. Jefferson J. Doyle1,*,
  4. Djahida Bedja3,
  5. YiChun Chen1,
  6. Christel van Erp1,
  7. Mark E. Lindsay1,2,
  8. David Kim1,
  9. Florian Schoenhoff1,
  10. Ronald D. Cohn1,2,
  11. Bart L. Loeys4,
  12. Craig J. Thomas5,
  13. Samarjit Patnaik5,
  14. Juan J. Marugan5,
  15. Daniel P. Judge6,
  16. Harry C. Dietz1,2,6,
  1. 1Howard Hughes Medical Institute and Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  2. 2Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  3. 3Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  4. 4Centre for Medical Genetics, Ghent University, 9000 Ghent, Belgium.
  5. 5National Institutes of Health Chemical Genomics Center, Rockville, MD 20850, USA.
  6. 6Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  1. To whom correspondence should be addressed. E-mail: hdietz{at}jhmi.edu.
  1. * These authors contributed equally to this work.

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