Research Article

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

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Science  12 Aug 2011:
Vol. 333, Issue 6044, pp. 850-856
DOI: 10.1126/science.1205669

Article Information

vol. 333 no. 6044 850-856

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History: 
  • Received for publication March 16, 2011
  • Accepted for publication July 1, 2011
  • .

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Author Information

  1. Davide Corti1,2,*,
  2. Jarrod Voss3,*,
  3. Steven J. Gamblin3,*,
  4. Giosiana Codoni1,*,
  5. Annalisa Macagno1,
  6. David Jarrossay1,
  7. Sebastien G. Vachieri3,
  8. Debora Pinna1,
  9. Andrea Minola1,
  10. Fabrizia Vanzetta2,
  11. Chiara Silacci1,
  12. Blanca M. Fernandez-Rodriguez1,
  13. Gloria Agatic2,
  14. Siro Bianchi2,
  15. Isabella Giacchetto-Sasselli1,
  16. Lesley Calder3,
  17. Federica Sallusto1,
  18. Patrick Collins3,
  19. Lesley F. Haire3,
  20. Nigel Temperton4,
  21. Johannes P. M. Langedijk5,,
  22. John J. Skehel3,,
  23. Antonio Lanzavecchia1,6,
  1. 1Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland.
  2. 2Humabs BioMed SA, 6500 Bellinzona, Switzerland.
  3. 3Medical Research Council (MRC) National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
  4. 4Viral Pseudotype Unit, School of Pharmacy, University of Kent, Kent ME4 4TB, UK.
  5. 5Pepscan Therapeutics BV, Lelystad, 8243 RC, Netherlands.
  6. 6Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, 8032 Zürich, Switzerland.
  1. To whom correspondence should be addressed. E-mail: lanzavecchia{at}irb.unisi.ch (A.L.); skeheljj{at}nimr.mrc.ac.uk (J.J.S.)
  1. * These authors contributed equally to this work.

  • Present address: Crucell Holland BV, 2333 CN Leiden, Netherlands.

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