Report

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

See allHide authors and affiliations

Science  26 Aug 2011:
Vol. 333, Issue 6046, pp. 1154-1157
DOI: 10.1126/science.1206923

Article Information

vol. 333 no. 6046 1154-1157

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 13, 2011
  • Accepted for publication July 5, 2011
  • .

Article Versions

Author Information

  1. Nishant Agrawal1,2,*,,
  2. Mitchell J. Frederick3,*,
  3. Curtis R. Pickering3,*,
  4. Chetan Bettegowda2,4,*,
  5. Kyle Chang5,
  6. Ryan J. Li1,
  7. Carole Fakhry1,
  8. Tong-Xin Xie3,
  9. Jiexin Zhang6,
  10. Jing Wang6,
  11. Nianxiang Zhang6,
  12. Adel K. El-Naggar7,
  13. Samar A. Jasser3,
  14. John N. Weinstein6,
  15. Lisa Treviño5,
  16. Jennifer A. Drummond5,
  17. Donna M. Muzny5,
  18. Yuanqing Wu5,
  19. Laura D. Wood8,
  20. Ralph H. Hruban8,
  21. William H. Westra8,
  22. Wayne M. Koch1,
  23. Joseph A. Califano1,9,
  24. Richard A. Gibbs5,9,
  25. David Sidransky1,
  26. Bert Vogelstein2,
  27. Victor E. Velculescu2,,
  28. Nickolas Papadopoulos2,
  29. David A. Wheeler5,
  30. Kenneth W. Kinzler2,,
  31. Jeffrey N. Myers3,
  1. 1Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
  2. 2Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA.
  3. 3Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe, Houston, TX 77030, USA.
  4. 4Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
  5. 5Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  6. 6Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe, Houston, TX 77030, USA.
  7. 7Department of Pathology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe, Houston, TX 77030, USA.
  8. 8Department of Pathology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
  9. 9Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, MD 21204, USA.
  10. 10Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  1. To whom correspondence should be addressed. E-mail: nagrawal{at}jhmi.edu (N.A.); velculescu{at}jhmi.edu (V.E.V.); kinzlke{at}jhmi.edu (K.W.K.); jmyers{at}mdanderson.org (J.N.M.)
  1. * These authors contributed equally to this work.

Altmetric

Article usage

Article usage: July 2011 to September 2019

AbstractFullPdf
Jul 2011379060
Aug 2011227376502302
Sep 20116818366869
Oct 20112402237436
Nov 20111546158378
Dec 2011922102251
Jan 2012962121259
Feb 201278795204
Mar 2012804110201
Apr 201266879175
May 201265884132
Jun 2012575114127
Jul 201248911784
Aug 201235510292
Sep 2012431140137
Oct 2012520134112
Nov 2012441127105
Dec 201235210386
Jan 201341312091
Feb 2013439144117
Mar 201341314995
Apr 2013453119117
May 2013370133104
Jun 201332611271
Jul 201342513675
Aug 20133258084
Sep 201337210294
Oct 201336110974
Nov 20133619181
Dec 20133399378
Jan 20143168860
Feb 201432010474
Mar 2014367106110
Apr 201439113284
May 20143547979
Jun 20142878682
Jul 20142618662
Aug 201427210876
Sep 20142419274
Oct 201434811089
Nov 201425310070
Dec 20142246056
Jan 20152469372
Feb 20152418152
Mar 20152639672
Apr 20152187160
May 20152386449
Jun 20152448269
Jul 20152146449
Aug 20151766766
Sep 20152956260
Oct 201523110171
Nov 20152605436
Dec 20152705751
Jan 20161834626
Feb 20162022745
Mar 20162383753
Apr 20162103362
May 20162254550
Jun 20162324731
Jul 20162304156
Aug 20162754455
Sep 20162794368
Oct 20162021532
Nov 20162642742
Dec 20162043228
Jan 20172123440
Feb 20172635258
Mar 20172202548
Apr 20171914041
May 20171762943
Jun 20171543941
Jul 20171612044
Aug 20171762434
Sep 20171551935
Oct 20172002630
Nov 20171672330
Dec 20171542141
Jan 20181892329
Feb 20181542333
Mar 20181182228
Apr 20181433738
May 20181504239
Jun 20184303137
Jul 20181291643
Aug 20185255242
Sep 20187573929
Oct 201813715542
Nov 20184886140
Dec 20181483124
Jan 20191246840
Feb 2019846429
Mar 2019988137
Apr 2019966742
May 2019586638
Jun 2019655626
Jul 2019795342
Aug 20191025732
Sep 2019492411