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The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

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Science  26 Aug 2011:
Vol. 333, Issue 6046, pp. 1157-1160
DOI: 10.1126/science.1208130

Article Information

vol. 333 no. 6046 1157-1160

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History: 
  • Received for publication May 10, 2011
  • Accepted for publication July 5, 2011
  • .

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Author Information

  1. Nicolas Stransky1,*,
  2. Ann Marie Egloff2,*,
  3. Aaron D. Tward1,3,4,*,
  4. Aleksandar D. Kostic1,5,
  5. Kristian Cibulskis1,
  6. Andrey Sivachenko1,
  7. Gregory V. Kryukov1,5,
  8. Michael S. Lawrence1,
  9. Carrie Sougnez1,
  10. Aaron McKenna1,
  11. Erica Shefler1,
  12. Alex H. Ramos1,
  13. Petar Stojanov1,
  14. Scott L. Carter1,
  15. Douglas Voet1,
  16. Maria L. Cortés1,
  17. Daniel Auclair1,
  18. Michael F. Berger1,
  19. Gordon Saksena1,
  20. Candace Guiducci1,
  21. Robert C. Onofrio1,
  22. Melissa Parkin1,
  23. Marjorie Romkes6,
  24. Joel L. Weissfeld7,
  25. Raja R. Seethala8,
  26. Lin Wang8,
  27. Claudia Rangel-Escareño9,
  28. Juan Carlos Fernandez-Lopez9,
  29. Alfredo Hidalgo-Miranda9,
  30. Jorge Melendez-Zajgla9,
  31. Wendy Winckler1,
  32. Kristin Ardlie1,
  33. Stacey B. Gabriel1,
  34. Matthew Meyerson1,5,10,11,
  35. Eric S. Lander1,5,12,
  36. Gad Getz1,
  37. Todd R. Golub1,5,11,13,14,,
  38. Levi A. Garraway1,5,10,11,,
  39. Jennifer R. Grandis2,15,
  1. 1The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  2. 2Department of Otolaryngology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
  3. 3Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02114, USA.
  4. 4Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
  5. 5Harvard Medical School, Boston, MA 02115, USA.
  6. 6Department of Medicine, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA.
  7. 7Department of Epidemiology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.
  8. 8Department of Pathology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
  9. 9Instituto Nacional de Medicina Genómica, Mexico City, 01900, Mexico.
  10. 10Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  11. 11Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  12. 12Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  13. 13Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  14. 14Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  15. 15Department of Pharmacology and Chemical Biology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
  1. To whom correspondence should be addressed. E-mail: levi_garraway{at}dfci.harvard.edu (L.A.G.); grandisjr{at}upmc.edu (J.R.G.)
  1. * These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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