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Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

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Science  02 Sep 2011:
Vol. 333, Issue 6047, pp. 1300-1303
DOI: 10.1126/science.1210597

Article Information

vol. 333 no. 6047 1300-1303

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Print ISSN: 
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History: 
  • Received for publication July 1, 2011
  • Accepted for publication July 11, 2011
  • .

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Author Information

  1. Shinsuke Ito1,2,*,
  2. Li Shen1,2,*,
  3. Qing Dai3,
  4. Susan C. Wu1,2,
  5. Leonard B. Collins4,
  6. James A. Swenberg2,4,
  7. Chuan He3,
  8. Yi Zhang1,2,
  1. 1Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599–7295, USA.
  2. 2Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599–7295, USA.
  3. 3Department of Chemistry and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA.
  4. 4Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599–7295, USA.
  1. To whom correspondence should be addressed. E-mail: yi_zhang{at}med.unc.edu
  1. * These authors contributed equally to this work.

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