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A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

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Science  20 Jan 2012:
Vol. 335, Issue 6066, pp. 348-353
DOI: 10.1126/science.1212728

Article Information

vol. 335 no. 6066 348-353

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 16, 2011
  • Accepted for publication November 22, 2011
  • .

Article Versions

Author Information

  1. Jessica D. Kessler1,2,
  2. Kristopher T. Kahle3,4,
  3. Tingting Sun1,
  4. Kristen L. Meerbrey1,2,
  5. Michael R. Schlabach3,
  6. Earlene M. Schmitt1,2,
  7. Samuel O. Skinner1,5,
  8. Qikai Xu3,
  9. Mamie Z. Li3,
  10. Zachary C. Hartman6,
  11. Mitchell Rao2,
  12. Peng Yu2,
  13. Rocio Dominguez-Vidana1,2,
  14. Anthony C. Liang3,
  15. Nicole L. Solimini3,
  16. Ronald J. Bernardi7,
  17. Bing Yu8,
  18. Tiffany Hsu1,2,
  19. Ido Golding1,5,
  20. Ji Luo8,
  21. C. Kent Osborne9,10,11,12,
  22. Chad J. Creighton9,13,
  23. Susan G. Hilsenbeck9,10,13,
  24. Rachel Schiff9,10,11,12,
  25. Chad A. Shaw2,
  26. Stephen J. Elledge3,*,
  27. Thomas F. Westbrook1,2,7,9,*
  1. 1Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  2. 2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  3. 3Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Division of Genetics, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  4. 4Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02115, USA.
  5. 5Department of Physics, University of Illinois, Urbana, IL 61801, USA.
  6. 6Department of Clinical Cancer Prevention, M.D. Anderson Cancer Center, Houston, TX 77030, USA.
  7. 7Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  8. 8Medical Oncology Branch, National Cancer Institute, Center Drive, Bethesda, MD 20892, USA.
  9. 9Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  10. 10The Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
  11. 11Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  12. 12Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  13. 13Division of Biostatistics, Baylor College of Medicine, Houston, TX 77030, USA.
  1. *To whom correspondence should be addressed. E-mail: thomasw{at}bcm.edu (T.F.W.); selledge{at}genetics.med.harvard.edu (S.J.E.)

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