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Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

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Science  27 Apr 2012:
Vol. 336, Issue 6080, pp. 489-493
DOI: 10.1126/science.1219328

Article Information

vol. 336 no. 6080 489-493

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History: 
  • Received for publication January 18, 2012
  • Accepted for publication March 6, 2012
  • .

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Author Information

  1. Torsten Olszak1,*,
  2. Dingding An2,*,
  3. Sebastian Zeissig3,
  4. Miguel Pinilla Vera4,
  5. Julia Richter5,
  6. Andre Franke6,
  7. Jonathan N. Glickman7,
  8. Reiner Siebert5,
  9. Rebecca M. Baron4,
  10. Dennis L. Kasper2,,
  11. Richard S. Blumberg1,
  1. 1Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  2. 2Channing Laboratory, Brigham and Women’s Hospital and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel 24105, Germany.
  4. 4Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  5. 5Institute of Human Genetics, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel 24105, Germany.
  6. 6Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel 24105, Germany.
  7. 7GI Pathology, Caris Diagnostics, Caris Life Sciences, Newton, MA 02464, USA.
  1. To whom correspondence should be addressed. E-mail: rblumberg{at}partners.org (R.S.B.); dennis_kasper{at}hms.harvard.edu (D.L.K.)
  1. * These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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