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Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

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Science  11 May 2012:
Vol. 336, Issue 6082, pp. 740-743
DOI: 10.1126/science.1217283

Article Information

vol. 336 no. 6082 740-743

DOI: 
https://doi.org/10.1126/science.1217283
PubMed: 
22582263
Published By: 
American Association for the Advancement of Science
Print ISSN: 
0036-8075
Online ISSN: 
1095-9203
History: 
  • Received for publication November 30, 2011
  • Accepted for publication March 15, 2012
  • .
Copyright & Usage: 
Copyright © 2012, American Association for the Advancement of Science

Author Information

  1. Alon Keinan1,*,
  2. Andrew G. Clark1,2
  1. 1Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA.
  2. 2Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
  1. ↵*To whom correspondence should be addressed. E-mail: ak735{at}cornell.edu

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  • Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

    By Alon Keinan, Andrew G. Clark

    Science : 740-743

    Genetic models that incorporate recent human population growth can better identify mutations in large samples.

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