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Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

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Science  18 May 2012:
Vol. 336, Issue 6083, pp. 934-937
DOI: 10.1126/science.1220671

Article Information

vol. 336 no. 6083 934-937

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History: 
  • Received for publication February 16, 2012
  • Accepted for publication April 13, 2012
  • .

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Author Information

  1. Michael J. Booth1,*,
  2. Miguel R. Branco2,3,*,
  3. Gabriella Ficz2,
  4. David Oxley4,
  5. Felix Krueger5,
  6. Wolf Reik2,3,,
  7. Shankar Balasubramanian1,6,7,
  1. 1Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  2. 2Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.
  3. 3Centre for Trophoblast Research, University of Cambridge, Cambridge CB2 3EG, UK.
  4. 4Proteomics Research Group, Babraham Institute, Cambridge CB22 3AT, UK.
  5. 5Bioinformatics Group, Babraham Institute, Cambridge CB22 3AT, UK.
  6. 6School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, UK.
  7. 7Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge CB2 0RE, UK.
  1. To whom correspondence should be addressed. E-mail: wolf.reik{at}babraham.ac.uk (W.R.); sb10031{at}cam.ac.uk (S.B.)
  1. * These authors contributed equally to this work.

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