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Science  07 Sep 2012:
Vol. 337, Issue 6099, pp. 1247
DOI: 10.1126/science.337.6099.1247-a


The TriStar2 microplate reader employs the new optical concept ALL-4-ONE, enabling luminescence, fluorescence, and absorbance measurements. TriStar2 is also capable of reading Förster Resonance Energy Transfer (FRET), Bioluminescence Resonance Energy Transfer (BRET), and BRET2. The instrument is characterized by a universal detector with extremely low noise for fluorescence and luminescence measurements and is also equipped with a photodiode for absorbance readings. Furthermore, optical filters can be used for luminescence measurements, enabling BRET and multicolored luciferase reporter gene applications. TriStar2 can be fitted with up to three reagent injectors and temperature controls for the microplate compartment. A reagent compartment at the front makes reagents easily accessible and allows them to be cooled by the addition of crushed ice when needed. For increased sample throughput, TriStar2 can be integrated into lab automation systems. Special reagent mounts provide secure fixation for small reagent vials and ensure complete consumption of reagents by the angle of inclination.


The PowderSafe Bulk Handling Enclosure fills the need for effective containment during bulk powder manipulation without the expense or space requirements of a traditional walk-in or free-standing enclosure. With a unique drum access port incorporated into the base of the enclosure, the drum can be raised and sealed to the access port, effectively extending the enclosure's containment area into the drum. When drum access is not required, the included access port cover can be used to seal the base, allowing for use as a standard balance enclosure. Designed to provide a turbulence-free airflow environment, PowderSafe Bulk Handling Enclosures move air in a horizontal pattern to maximize containment while minimizing sample loss and balance instability. Proprietary HEPASafe filter change-out technology, incorporated into each PowderSafe Bulk Handling Enclosure, allows the operator to safely and effectively change both the prefilter and primary HEPA filter.


The advanced Bi-O-Vision Series transilluminators feature two workstations, producing both 312 nm ultraviolet (UV) and white light. The TD-1000R model offers fixed-intensity control, while the TVD-1000R model offers variable-intensity control of either UV or white light. These units are continuously adjustable from 100% down to 50%. This enables life science researchers to select the exact ultraviolet or white-light illumination needed to photodocument samples with a single piece of equipment. The UVB (312 nm) intensity of the TVD-1000R can be varied. This flexibility in irradiance control helps ensure the longest sample preparation time, while minimizing actual UV damage to the sample. The Bi-O-Vision has two adjacent workstations. The UV side is lit by five 8 W UVB tubes and delivers nanogram sensitivity for detecting ethidium bromide-stained DNA or RNA. The white-light side has three 8 W fluorescent tubes that ensure excellent illumination for viewing Coomassie blue-stained protein gels, methylene blue-stained DNA gels, and autoradiograms.


Bovine and ovine Dendritic Cell Growth Kits have been developed to improve dendritic cell (DC) generation by enabling researchers to develop a method for consistent cell generation, and to save time with prevalidated, optimized species-specific reagents. A complementary panel of antibodies for bovine and ovine DC markers has been launched to enable cell surface phenotyping of DCs. The Dendritic Cell Growth Kits are unique to AbD Serotec and were developed in collaboration with the Moredun Research Institute, Edinburgh, and the Institute for Animal Health, Compton, centers recognized worldwide for their research on the infectious diseases of livestock. The kits contain biologically active cytokines in liquid format, premixed at optimal concentrations to facilitate the generation of DCs from peripheral blood mononuclear cells.


A range of multiwell filtration microplates have been optimized for applications including cell harvesting, DNA separations, binding studies, plasmid isolation, general filtration, and sample cleanup. Included within the range are filtration plates that can simultaneously filter 96 or 384 samples of up to 350 μl volume, providing great productivity benefits and high filtered sample integrity. For larger volume applications (up to 5 ml/well), a choice of 48-well filtration plates are available. A broad range of filtration media including glass fiber, nylon, polyvinylidene fluoride (PVDF), and polyethylene allows control of filtration plate flow rates and retention characteristics to best suit many applications. Manufactured to the standard ANSI/SBS footprint, all Porvair filtration plates are fully automation compatible. Each well on the filtration plates has an individual drainage spout ensuring 100% sample transfer and zero crossover contamination. Manufactured from ultrapure grade polypropylene—all filtration plates minimize leachates when used with most common solvents.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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