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Highly Conserved Protective Epitopes on Influenza B Viruses

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Science  14 Sep 2012:
Vol. 337, Issue 6100, pp. 1343-1348
DOI: 10.1126/science.1222908

Article Information

vol. 337 no. 6100 1343-1348

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History: 
  • Received for publication April 4, 2012
  • Accepted for publication July 9, 2012
  • .

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Author Information

  1. Cyrille Dreyfus1,*,
  2. Nick S. Laursen1,2,*,
  3. Ted Kwaks3,
  4. David Zuijdgeest3,
  5. Reza Khayat1,
  6. Damian C. Ekiert1,,
  7. Jeong Hyun Lee1,
  8. Zoltan Metlagel1,,
  9. Miriam V. Bujny3,
  10. Mandy Jongeneelen3,
  11. Remko van der Vlugt3,
  12. Mohammed Lamrani3,
  13. Hans J. W. M. Korse3,
  14. Eric Geelen3,
  15. Özcan Sahin3,
  16. Martijn Sieuwerts3,
  17. Just P. J. Brakenhoff3,
  18. Ronald Vogels3,
  19. Olive T. W. Li4,
  20. Leo L. M. Poon4,
  21. Malik Peiris4,
  22. Wouter Koudstaal3,
  23. Andrew B. Ward1,
  24. Ian A. Wilson1,5,§,
  25. Jaap Goudsmit3,§,
  26. Robert H. E. Friesen3
  1. 1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  2. 2Department of Molecular Biology, Gustav Wieds Vej 10C, Aarhus 8000, Denmark.
  3. 3Crucell Vaccine Institute, Janssen Center of Excellence for Immunoprophylaxis, Archimedesweg 4-6, 2301 CA Leiden, Netherlands.
  4. 4State Key Laboratory of Emerging Infectious Diseases and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China.
  5. 5Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  1. §To whom correspondence should be addressed. E-mail: wilson{at}scripps.edu (I.A.W.); jaap.goudsmit{at}crucell.com (J.G.)
  1. * These authors contributed equally to this work.

  • Present address: Department of Microbiology and Immunology, University of California—San Francisco, 600 16th Street, San Francisco, CA 94143, USA.

  • Present address: Lawrence Berkeley National Laboratory, Department of Bioenergy/GTL and Structural Biology, Berkeley, CA 94720, USA.

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