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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

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Science  21 Sep 2012:
Vol. 337, Issue 6101, pp. 1541-1546
DOI: 10.1126/science.1221711

Article Information

vol. 337 no. 6101 1541-1546

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Online ISSN: 
History: 
  • Received for publication March 9, 2012
  • Accepted for publication July 25, 2012
  • .

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Author Information

  1. Anwesha Dey1,
  2. Dhaya Seshasayee2,
  3. Rajkumar Noubade2,
  4. Dorothy M. French3,
  5. Jinfeng Liu4,
  6. Mira S. Chaurushiya1,
  7. Donald S. Kirkpatrick5,
  8. Victoria C. Pham5,
  9. Jennie R. Lill5,
  10. Corey E. Bakalarski4,
  11. Jiansheng Wu5,
  12. Lilian Phu5,
  13. Paula Katavolos6,
  14. Lindsay M. LaFave7,
  15. Omar Abdel-Wahab7,
  16. Zora Modrusan8,
  17. Somasekar Seshagiri8,
  18. Ken Dong9,
  19. Zhonghua Lin10,
  20. Mercedesz Balazs10,
  21. Rowena Suriben1,
  22. Kim Newton1,
  23. Sarah Hymowitz9,
  24. Guillermo Garcia-Manero11,
  25. Flavius Martin2,
  26. Ross L. Levine7,
  27. Vishva M. Dixit1,*
  1. 1Department of Physiological Chemistry, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  2. 2Department of Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  3. 3Department of Pathology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  4. 4Department of Bioinformatics and Computational Biology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  5. 5Department of Protein Chemistry, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  6. 6Department of Safety Assessment, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  7. 7Human Oncology and Pathogenesis Program and Leukemia Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  8. 8Department of Molecular Biology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  9. 9Department of Structural Biology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  10. 10Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  11. 11MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
  1. *To whom correspondence should be addressed. E-mail: dixit{at}gene.com

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