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Type I Interferon Suppresses Type II Interferon–Triggered Human Anti-Mycobacterial Responses

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Science  22 Mar 2013:
Vol. 339, Issue 6126, pp. 1448-1453
DOI: 10.1126/science.1233665

Article Information

vol. 339 no. 6126 1448-1453

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 5, 2012
  • Accepted for publication January 29, 2013

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Author Information

  1. Rosane M. B. Teles1,
  2. Thomas G. Graeber4,
  3. Stephan R. Krutzik1,
  4. Dennis Montoya1,
  5. Mirjam Schenk1,
  6. Delphine J. Lee5,
  7. Evangelia Komisopoulou4,
  8. Kindra Kelly-Scumpia1,
  9. Rene Chun3,
  10. Shankar S. Iyer2,
  11. Euzenir N. Sarno6,
  12. Thomas H. Rea7,
  13. Martin Hewison3,
  14. John S. Adams3,
  15. Stephen J. Popper8,
  16. David A. Relman8,9,
  17. Steffen Stenger10,
  18. Barry R. Bloom11,
  19. Genhong Cheng2,
  20. Robert L. Modlin1,2,*
  1. 1Division of Dermatology, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA.
  2. 2Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA.
  3. 3UCLA/Orthopedic Hospital Department of Orthopedic Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA.
  4. 4Crump Institute for Molecular Imaging, Institute for Molecular Medicine, Johnson Comprehensive Cancer Center, California NanoSystems Institute, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.
  5. 5Department of Translational Immunology, John Wayne Cancer Institute, Santa Monica, CA, USA.
  6. 6Department of Mycobacteriosis, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.
  7. 7Department of Dermatology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA.
  8. 8Department of Microbiology and Immunology and Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  9. 9Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.
  10. 10Institute for Medical Microbiology and Hygiene, University Hospital of Ulm, Germany.
  11. 11Harvard School of Public Health, Boston, MA 02115, USA.
  1. *Corresponding author. E-mail: rmodlin{at}mednet.ucla.edu

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