Research Article

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

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Science  10 May 2013:
Vol. 340, Issue 6133, pp. 711-716
DOI: 10.1126/science.1234150

Article Information

vol. 340 no. 6133 711-716

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History: 
  • Received for publication December 17, 2012
  • Accepted for publication March 15, 2013

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Author Information

  1. Joseph Jardine1,2,3,4,*,
  2. Jean-Philippe Julien2,3,5,*,
  3. Sergey Menis1,2,3,4,*,
  4. Takayuki Ota1,
  5. Oleksandr Kalyuzhniy1,2,3,4,
  6. Andrew McGuire6,
  7. Devin Sok1,2,3,
  8. Po-Ssu Huang4,
  9. Skye MacPherson1,2,3,4,
  10. Meaghan Jones1,2,4,
  11. Travis Nieusma2,3,5,
  12. John Mathison1,
  13. David Baker4,
  14. Andrew B. Ward2,3,5,
  15. Dennis R. Burton1,2,3,7,
  16. Leonidas Stamatatos6,8,
  17. David Nemazee1,
  18. Ian A. Wilson2,3,5,9,
  19. William R. Schief1,2,3,4,
  1. 1Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  5. 5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  6. 6Seattle Biomedical Research Institute, Seattle, WA 98109, USA.
  7. 7Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA 02129, USA.
  8. 8Department of Global Health, University of Washington, Seattle, WA 98109, USA.
  9. 9Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  1. Corresponding author. E-mail: schief{at}scripps.edu
  1. * These authors contributed equally to this work.

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