Report

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

See allHide authors and affiliations

Science  31 May 2013:
Vol. 340, Issue 6136, pp. 1100-1106
DOI: 10.1126/science.1232044

Article Information

vol. 340 no. 6136 1100-1106

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 26, 2012
  • Accepted for publication April 5, 2013

Author Information

  1. Liron Bar-Peled1,2,*,
  2. Lynne Chantranupong1,2,*,
  3. Andrew D. Cherniack4,
  4. Walter W. Chen1,2,
  5. Kathleen A. Ottina1,2,
  6. Brian C. Grabiner1,2,
  7. Eric D. Spear7,
  8. Scott L. Carter4,
  9. Matthew Meyerson4,5,6,
  10. David M. Sabatini1,2,3,4,
  1. 1Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology, 9 Cambridge Center, Cambridge, MA 02142, USA.
  2. 2Koch Institute for Integrative Cancer Research, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  3. 3Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  4. 4Broad Institute of Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Cambridge, MA 02142, USA.
  5. 5Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA.
  6. 6Department of Pathology, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
  7. 7Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  1. Corresponding author. E-mail: sabatini{at}wi.mit.edu
  1. * These authors contributed equally to this work

Altmetric

Article usage

Article usage: May 2013 to July 2019

AbstractFullPdf
May 2013110586411167
Jun 20131281917601869
Jul 20131619569710
Aug 2013780273231
Sep 2013672261251
Oct 2013575209182
Nov 2013459214149
Dec 2013342165210
Jan 2014332152111
Feb 201427015296
Mar 2014261140114
Apr 2014284155162
May 20142048957
Jun 201418210559
Jul 201420611288
Aug 20141046861
Sep 201413810278
Oct 2014212145124
Nov 201414612385
Dec 201421110173
Jan 20151538689
Feb 201510711954
Mar 2015133127111
Apr 20151237756
May 20151226854
Jun 20151107043
Jul 20151129257
Aug 20158010249
Sep 2015727143
Oct 20151149962
Nov 20151309153
Dec 20151067659
Jan 20161353740
Feb 20161744072
Mar 20162444986
Apr 20161975879
May 20162135592
Jun 20161964361
Jul 20161834843
Aug 20162314480
Sep 20161794066
Oct 20162023857
Nov 20161953742
Dec 20161523026
Jan 20171813861
Feb 20171975855
Mar 20171953870
Apr 20171773665
May 20171472449
Jun 20171462746
Jul 20171362937
Aug 20171231847
Sep 20171322741
Oct 20171502841
Nov 20171823559
Dec 20171543838
Jan 20181613384
Feb 20181381942
Mar 20181655161
Apr 20181282339
May 20181804298
Jun 20181212534
Jul 20181103057
Aug 2018726856
Sep 2018638359
Oct 2018687744
Nov 2018729248
Dec 2018676732
Jan 2019608743
Feb 2019968141
Mar 201910511049
Apr 2019717838
May 20195913764
Jun 20198011430
Jul 2019263722