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Does Cloning Produce Better Embryonic Stem Cells?

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Science  21 Jun 2013:
Vol. 340, Issue 6139, pp. 1390
DOI: 10.1126/science.340.6139.1390

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Shoukhrat Mitalipov last week sought to allay fears his group had not created cloned human embryonic stem cells by laying out his evidence for them at the annual meeting of the International Society for Stem Cell Research. Perhaps more provocative, he also showed the first data hinting that such cells may trump another kind of stem cell now in vogue, induced pluripotent stem (iPS) cells. Mitalipov said that compared with iPS cells, his cells bear "fewer abnormalities" and "more closely resemble genuine embryonic stem cells," traits that may favor their use as therapies for particular conditions, such as diseases of a cell's energy-producing mitochondria.

  • * Trisha Gura is a science writer in Boston.

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