Report

MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility

See allHide authors and affiliations

Science  05 Jul 2013:
Vol. 341, Issue 6141, pp. 71-73
DOI: 10.1126/science.1237999

You are currently viewing the editor's summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Female Infertility

Anovulation, the failure of a woman's ovary to release an oocyte, is a major cause of female infertility. The mechanisms of ovulation have been studied extensively, with the hypothalamicpituitary axis serving as a key player in its regulation. Hasuwa et al. (p. 71, published online 13 June) describe a mechanism by which anovulation can be caused by the disruption of two microRNAs that are expressed in the pituitary gland.

View Full Text