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When Mice Mislead

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Science  22 Nov 2013:
Vol. 342, Issue 6161, pp. 922-925
DOI: 10.1126/science.342.6161.922

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Lots of mice line up at an experiment's starting line, but not all of them make it to the finish. That's just one of the flaws that bedevils animal studies—and, some say, a reason why these experiments often don't pan out in people. There's a push to raise standards and openness in the vast universe of animal research, and hope that doing so will not only improve the quality of science, but also its image in the public eye.