Research Article

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

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Science  20 Dec 2013:
Vol. 342, Issue 6165, pp. 1477-1483
DOI: 10.1126/science.1245625

Article Information

vol. 342 no. 6165 1477-1483

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History: 
  • Received for publication September 6, 2013
  • Accepted for publication October 7, 2013
  • .

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Author Information

  1. Jean-Philippe Julien1,2,3,
  2. Albert Cupo4,
  3. Devin Sok2,3,5,
  4. Robyn L. Stanfield1,2,3,
  5. Dmitry Lyumkis1,6,
  6. Marc C. Deller7,
  7. Per-Johan Klasse4,
  8. Dennis R. Burton2,3,5,8,
  9. Rogier W. Sanders4,9,
  10. John P. Moore4,*,
  11. Andrew B. Ward1,2,3,*,
  12. Ian A. Wilson1,2,3,7,10,*
  1. 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Weill Medical College of Cornell University, New York, NY 10021, USA.
  5. 5Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
  6. 6National Resource for Automated Molecular Microscopy, The Scripps Research Institute, La Jolla, CA 92037, USA.
  7. 7Joint Center for Structural Genomics, The Scripps Research Institute, La Jolla, CA 92037, USA.
  8. 8Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02129, USA.
  9. 9Department of Medical Microbiology, Academic Medical Center, Amsterdam, Netherlands.
  10. 10Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  1. *Corresponding author. E-mail: wilson{at}scripps.edu (I.A.W.); abward{at}scripps.edu (A.B.W.); jpm2003{at}med.cornell.edu (J.P.M.)

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