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Genetic Screens in Human Cells Using the CRISPR-Cas9 System

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Science  03 Jan 2014:
Vol. 343, Issue 6166, pp. 80-84
DOI: 10.1126/science.1246981

Article Information

vol. 343 no. 6166 80-84

PubMed: 
Print ISSN: 
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History: 
  • Received for publication October 8, 2013
  • Accepted for publication December 2, 2013
  • .

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Author Information

  1. Tim Wang1,2,3,4,
  2. Jenny J. Wei1,2,
  3. David M. Sabatini1,2,3,4,5,*,,
  4. Eric S. Lander1,3,6,*,
  1. 1Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
  2. 2Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.
  3. 3Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA.
  4. 4David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  5. 5Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, MA 02139, USA.
  6. 6Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  1. *Corresponding author. E-mail: sabatini{at}wi.mit.edu (D.M.S.); lander{at}broadinstitute.org (E.S.L.)
  1. These authors contributed equally to this work.

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