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Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

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Science  18 Apr 2014:
Vol. 344, Issue 6181, pp. 304-307
DOI: 10.1126/science.1248571

Article Information

vol. 344 no. 6181 304-307

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History: 
  • Received for publication November 15, 2013
  • Accepted for publication March 26, 2014
  • .

Author Information

  1. Hiroshi Suzuki1,*,
  2. Tomohiro Nishizawa2,3,*,
  3. Kazutoshi Tani1,*,
  4. Yuji Yamazaki4,,
  5. Atsushi Tamura4,
  6. Ryuichiro Ishitani2,3,
  7. Naoshi Dohmae3,
  8. Sachiko Tsukita4,
  9. Osamu Nureki2,3,,
  10. Yoshinori Fujiyoshi1,5,
  1. 1Cellular and Structural Physiology Institute, Nagoya University, Chikusa, Nagoya 464-8601, Japan.
  2. 2Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Bunkyo, Tokyo 113-0032, Japan.
  3. 3Global Research Cluster, RIKEN, Wako, Saitama 351-0198, Japan.
  4. 4Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, Japan.
  5. 5Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan.
  1. Corresponding author. E-mail: nureki{at}bs.s.u-tokyo.ac.jp (O.N.); yoshi{at}cespi.nagoya-u.ac.jp (Y.F.)
  1. * These authors contributed equally to this work.

  • Present address: Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.

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