Technical Comments

Comment on “Revealing Nature’s Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA”

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Science  09 May 2014:
Vol. 344, Issue 6184, pp. 578
DOI: 10.1126/science.1251248

Abstract

Brunecky et al. (Reports, 20 December 2013, p. 1513) compared the cellulolytic activity of bacterial multimodular cellulase CelA with fungal Cel7A (cellobiohydrolase I from Trichoderma reesei). If more active Cel7A from another fungus were used as a reference enzyme under optimal conditions with β-glucosidase added, the reported difference between bacterial and fungal enzymes would be less dramatic.

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