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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

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Science  20 Jun 2014:
Vol. 344, Issue 6190, pp. 1396-1401
DOI: 10.1126/science.1254257

Article Information

vol. 344 no. 6190 1396-1401

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History: 
  • Received for publication April 2, 2014
  • Accepted for publication May 30, 2014
  • .

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Author Information

  1. Anoop P. Patel*,1,2,3,4,
  2. Itay Tirosh*,3,
  3. John J. Trombetta3,
  4. Alex K. Shalek3,
  5. Shawn M. Gillespie2,3,4,
  6. Hiroaki Wakimoto1,
  7. Daniel P. Cahill1,
  8. Brian V. Nahed1,
  9. William T. Curry1,
  10. Robert L. Martuza1,
  11. David N. Louis2,
  12. Orit Rozenblatt-Rosen3,
  13. Mario L. Suvà2,3,,
  14. Aviv Regev3,4,5,,
  15. Bradley E. Bernstein2,3,4,
  1. 1Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  2. 2Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  3. 3Broad Institute of Harvard and Massachusetts Institute of Techonology (MIT), Cambridge, MA 02142, USA.
  4. 4Howard Hughes Medical Institute Chevy Chase, MD 20815, USA.
  5. 5Department of Biology, MIT, Cambridge, MA 02139, USA.
  1. Corresponding author. E-mail: bernstein.bradley{at}mgh.harvard.edu (B.E.B.); aregev{at}broadinstitute.org (A.R.); suva.mario{at}mgh.harvard.edu (M.L.S.)
  1. * These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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