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Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex

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Science  20 Jun 2014:
Vol. 344, Issue 6190, pp. 1405-1410
DOI: 10.1126/science.1253823

Article Information

vol. 344 no. 6190 1405-1410

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 24, 2014
  • Accepted for publication May 27, 2014
  • .

Author Information

  1. Kwangkook Lee1,
  2. Xiaofen Zhong2,
  3. Shenyan Gu1,
  4. Anna Magdalena Kruel3,
  5. Martin B. Dorner4,
  6. Kay Perry5,
  7. Andreas Rummel3,
  8. Min Dong2,
  9. Rongsheng Jin1,*
  1. 1Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA.
  2. 2Department of Microbiology and Immunobiology, Harvard Medical School, Division of Neuroscience, New England Primate Research Center, Southborough, MA 01772, USA.
  3. 3Institut für Toxikologie, Medizinische Hochschule Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.
  4. 4Centre for Biological Threats and Special Pathogens–Biological Toxins (ZBS3), Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany.
  5. 5Northeastern Collaborative Access Team (NE-CAT) and Department of Chemistry and Chemical Biology, Cornell University, Building 436E, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA.
  1. *Corresponding author. E-mail: r.jin{at}uci.edu

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