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Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

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Science  11 Jul 2014:
Vol. 345, Issue 6193, pp. 216-220
DOI: 10.1126/science.1253533

Article Information

vol. 345 no. 6193 216-220

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 18, 2014
  • Accepted for publication June 10, 2014

Author Information

  1. Min Yu1,2,*,
  2. Aditya Bardia1,3,
  3. Nicola Aceto1,
  4. Francesca Bersani1,
  5. Marissa W. Madden1,
  6. Maria C. Donaldson1,
  7. Rushil Desai1,
  8. Huili Zhu1,
  9. Valentine Comaills1,
  10. Zongli Zheng1,4,5,
  11. Ben S. Wittner1,
  12. Petar Stojanov6,
  13. Elena Brachtel4,
  14. Dennis Sgroi1,4,
  15. Ravi Kapur7,
  16. Toshihiro Shioda1,3,
  17. David T. Ting1,3,
  18. Sridhar Ramaswamy1,3,
  19. Gad Getz1,4,6,
  20. A. John Iafrate1,4,
  21. Cyril Benes1,3,
  22. Mehmet Toner7,8,
  23. Shyamala Maheswaran1,8,,
  24. Daniel A. Haber1,2,3,
  1. 1Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.
  2. 2Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  3. 3Department of Medicine, Harvard Medical School, Charlestown, MA 02129, USA.
  4. 4Department of Pathology, Harvard Medical School, Charlestown, MA 02129, USA.
  5. 5Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
  6. 6Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  7. 7Center for Bioengineering in Medicine, Harvard Medical School, Charlestown, MA 02129, USA.
  8. 8Department of Surgery, Harvard Medical School, Charlestown, MA 02129, USA.
  1. Corresponding author. E-mail: maheswaran{at}helix.mgh.harvard.edu (S.M.); haber{at}helix.mgh.harvard.edu (D.A.H.)
  • * Present address: Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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