Contents
Vol 345, Issue 6194
Special Issue
Slicing the Wheat Genome
Introduction to special issue
Research Articles
Contents
This Week in Science
Editorial
Editors' Choice
Podcasts
- Science Podcast: 18 July Show
On this week's show: A new tech to alter genes in the wild and a roundup of stories from our daily news site.
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- A radical change in peer review
A pilot project to ease pressure on NSF's vaunted peer-review system required grant applicants to review seven competing proposals.
- Proteins and a pregnancy woe
Surprising insight into preeclampsia may offer early warning for at-risk women.
- Researchers aim for an electrical memory prosthesis
DARPA-funded effort to develop implants for traumatic brain injuries draws skepticism.
- Harvest of genome data for wheat growers
DNA survey orders genes, edging closer to the deciphering of this complex crop.
Feature
- The elusive heart fix
After years of hope and hype, researchers still don't agree whether cell infusions rejuvenate the human heart.
- Top heart lab comes under fire
A high-profile heart research lab is in the spotlight while under investigation by Harvard Medical School.
Working Life
Letters
Books et al.
Policy Forum
- NIH Roadmap/Common Fund at 10 years
A mechanism for funding biomedical research at NIH that transcends Institute and Center boundaries is bearing fruit
Perspectives
- The future lies in uncertainty
Sophisticated statistical insights are crucial for gaining knowledge from ever-larger data sets
- Mind the midzone
Is the separation of chromosomes during cell division monitored by a checkpoint?
- Charge transfer goes the distance
Electronic relaxation following x-ray excitation illuminates steps in molecular dissociation.
- Improving cardiac rhythm with a biological pacemaker
Heart muscle cells in a large animal model are reprogrammed to restore heart rate and function
- Creating antioxidants by oxidation catalysis
A key component of vitamin E can be synthesized without use of expensive transition metal catalysts.
- One, two, three, cytoplasmic dynein is go!
The dynein motor protein must be part of a three-way complex to be fully active.
- Quantum systems under control
Optical trapping enables the building of quantum matter one atom at a time.
- Walter Gehring (1939–2014)
A brief reflection on the life and lab of a preeminent developmental biologist
Review
Reports
- Imaging charge transfer in iodomethane upon x-ray photoabsorption
A free-electron laser enables precise tracking of electron movement between segments of a dissociating molecule.
- High-turnover hypoiodite catalysis for asymmetric synthesis of tocopherols
An iodide salt with a chiral counterion proves an efficient catalyst for preparation of compounds analogous to vitamin E.
- A hole-conductor–free, fully printable mesoscopic perovskite solar cell with high stability
A mixed organic phase perovskite grown in mesoporous templates boosts solar cell stability.
- Dielectric gradient metasurface optical elements
Silicon-based metasurfaces can extend the range of planar optical devices.
- Quantum computations on a topologically encoded qubit
A protocol is implemented that allows for fault-tolerant quantum computing.
- Two-particle quantum interference in tunnel-coupled optical tweezers
Two bosonic rubidium atoms in coupled quantum wells are prepared in a symmetrical state and allowed to interfere.
- Electro-optical frequency division and stable microwave synthesis
Two closely spaced laser lines can be used for the generation of stable microwaves.
- Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans
Calsyntenin-dependent activation of insulin-PI3K signaling in the synaptic region governs associative learning.
- Thermohaline circulation crisis and impacts during the mid-Pleistocene transition
Marine thermohaline circulation changed markedly during the mid-Pleistocene transition.
- Oceanic mass transport by mesoscale eddies
Mesoscale eddies transport as much ocean water as is moved by wind and thermohaline circulation.
- Leverage points for improving global food security and the environment
A limited set of interventions could disproportionately improve crop production and environmental sustainability.
- Human tRNA synthetase catalytic nulls with diverse functions
Alternative splicing of aminoacyl transfer RNA synthetases ablates the catalytic domain to yield diverse alternative functions.
- Feedback control of chromosome separation by a midzone Aurora B gradient
A mitotic spindle midzone-associated Aurora B gradient monitors chromosome separation during cell division.
- Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes
Single-molecule studies reveal a mechanism to activate the molecular motor cytoplasmic dynein in a cargo-specific manner.
