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Human tRNA synthetase catalytic nulls with diverse functions

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Science  18 Jul 2014:
Vol. 345, Issue 6194, pp. 328-332
DOI: 10.1126/science.1252943

Article Information

vol. 345 no. 6194 328-332

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History: 
  • Received for publication March 5, 2014
  • Accepted for publication June 18, 2014

Author Information

  1. Wing-Sze Lo1,2,
  2. Elisabeth Gardiner3,4,
  3. Zhiwen Xu1,2,
  4. Ching-Fun Lau1,2,
  5. Feng Wang1,2,
  6. Jie J. Zhou1,2,
  7. John D. Mendlein4,
  8. Leslie A. Nangle4,
  9. Kyle P. Chiang4,
  10. Xiang-Lei Yang1,3,
  11. Kin-Fai Au5,
  12. Wing Hung Wong6,
  13. Min Guo7,
  14. Mingjie Zhang1,8,
  15. Paul Schimmel1,3,7,*
  1. 1IAS HKUST–Scripps R&D Laboratory, Institute for Advanced Study, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
  2. 2Pangu Biopharma, Edinburgh Tower, The Landmark, 15 Queen’s Road Central, Hong Kong, China.
  3. 3The Scripps Laboratories for tRNA Synthetase Research, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA 92037, USA.
  4. 4aTyr Pharma, 3545 John Hopkins Court, Suite 250, San Diego, CA 92121, USA.
  5. 5Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.
  6. 6Department of Statistics, Stanford University, Stanford, CA 94305, USA.
  7. 7The Scripps Laboratories for tRNA Synthetase Research, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA.
  8. 8Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
  1. *Corresponding author. E-mail: schimmel{at}scripps.edu

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